Na CMC content. As the Na CMC content increases the swelling index also increased. Buccal tablets of Valsartan using various suitable bioadhesive polymers such as CP 934, hpmc K4M, and Na CMC. The formulation F3 was considered as the optimized formulation based on satisfactory bioadhesive strength, In-vitro dissolution drug release.69.95, In-vitro drug diffusion.66.68 for. The prepared tablets were characterized by swelling studies, matrix erosion, surface pH, bioadhesive properties, In-vitro drug dissolution and In-vitro diffusion studies. Abstract, pDF, share this). Author(s bismarck essays Anup Kumar Roy, Vinod kumar sm, Syed Jalaluddin Basha, Rabiul Haque, Roopa Karki. The surface pH of all formulations was found to be satisfactory, and values were in between the range of 5-7 pH, hence no irritation to buccal cavity is assumed. The drug release was found to be zero order release. Tablets containing CP: hpmc in the ratio 1:3 has shown maximum percentage of In-vitro drug release as well as In-vivo diffusion through buccal mucosa.
Buccal tablets thesis pdf
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